
A third long road trip in four weeks will play into the Bills' demise this Sunday. Even without Anquan Boldin, pick Arizona in this matchup when the Cardinals host Buffalo.
At first glance, the Buffalo Bills might seem like the right play. They are 4-0 with outstanding special teams, excellent team chemistry and an improving offense, while the Cardinals are coming off a game where they gave up 56 points and probably will be without Anquan Boldin.
First looks can be deceiving, though.
The Cardinals are going to win this game, which is all you need to cash since Arizona is in the pick'em to minus-one range. The Bills are making their third long road trip in four weeks. They are a carpet team playing on grass. Buffalo is improved. However, the Bills' schedule has laid out extremely well up to this point.
The Bills hosted a crippled Seattle squad opening week when the Seahawks weren't ready. Buffalo then drew Jacksonville, which was struggling with a cluster injury problem in its offensive line. Buffalo barely nipped Oakland, winning by one point at home. Then last week the Bills beat maybe the worst team in the NFL, the St. Louis Rams. So the Bills' 4-0 mark isn't as strong as it may look.
The Cardinals return home after being out East for two straight weeks. They are anxious to put the embarrassement of last Sunday's loss to the New York Jets behind them. The Bills last played in Arizona in 1999. Despite a boatload of turnovers against the Jets, Arizona quarterback Kurt Warner is having a strong season ranking third in passing yards and fifth in quarterback ratings.
Yes, the Cardinals probably aren't going to have Boldin. However, they still have an "A" wideout in Larry Fitzgerald and young, talented wide receivers to attack a youthful Bills secondary that most likely is going to be without injured starting cornerback Terrence McGee.
The Bills are limping into their bye, which comes up next week. In addition to probably missing McGee, they will be without Roscoe Parrish. These losses hurt their vaunted special teams. Buffalo's two best defensive lineman, Marcus Stroud and Aaron Schobel, also are banged-up.
Arizona should be able to put up at least 21 points at home against the Bills. The Cardinals are 10-5 when scoring 21 or more points.
A lot is being made of Boldin getting hurt. But beneath the radar screen is the news that the Cardinals should get back two key defensive players. Nose tackle Gabe Watson is set to make his season debut after being out with a knee injury and strong safety Adrian Wilson is expected to play after missing last week's game because of a hamstring injury.
Free Pick: Cardinals Pick 'Em (-110)