The MLB playoff races are heating up as we move into the third weekend of August.  Let’s take a closer look at three games in the Senior Circuit from a betting perspective and decide where we should place our MLB picks.

New York Mets at Washington Nationals

Bryce HarperThe Washington Nationals enjoyed an off day after going 8-2 on their recently completed 10-game road trip, which helped to push their record to a major league-best 12-4 in August.  The New York Mets came away with an 8-4 win over the Cincinnati Reds as +138 road underdogs on Thursday night, but have failed to win consecutive games since the first two days of the month.

Mets starting pitcher Johan Santana (6-8, 4.58 ERA) pitched a career low-tying 1.1 innings in his first start off the disabled list in a 9-3 home loss to the Atlanta Braves, allowing eight runs and eight hits in the process.  The left-hander hasn’t enjoyed much success away from Citi Field this year, posting a 2-4 record and 5.36 ERA in nine road starts, surrendering eight home runs in 48.2 combined frames.  In 10 career outings versus the Nationals, Santana is 6-3 with a 2.91 ERA. 

Ross Detwiler (6-5, 3.18 ERA) is the least talked about pitcher in the Nationals starting rotation, but he’s putting together a solid 2012 campaign.  The left-hander is 5-1 with a 2.51 ERA in 12 home appearances (nine starts), serving up just four round trippers in 61 combined innings.  In eight lifetime appearances (five starts) versus the Mets, Detwiler has produced a 3-1 record and 2.81 ERA, which includes a no-decision effort in leading the club to a 5-4 home win on July 17 in the series (7 IP, 5 H).

When it comes to making our MLB picks, us bettors should be confident in laying this number with the Nationals against Santana, as they’ve won 16 of the last 21 meetings.

MLB Picks:  Washington Nationals -160 

Arizona Diamondbacks at Houston Astros

Arizona hit two solo home runs in the top of the ninth inning to come away with a 2-1 road victory over the St. Louis Cardinals on Thursday night, which is the type of victory that may start a long winning streak.  Houston is the perfect team to open a three-game series against, as the club has compiled a 7-37 record in its last 44 games. 

Diamondbacks starting pitcher Wade Miley (12-8, 3.02 ERA) has been handed consecutive defeats in facing the Pittsburgh Pirates and Washington Nationals, but has a chance to bounce back in a big way in this spot.  The left-hander earned a 12-3 home win over the Astros on July 21, allowing just a single run and four hits over seven frames.  

Dallas Keuchel (1-4, 5.29 ERA) has failed to earn a victory since June 23, with the club falling in defeat in six of his last seven outings.  The 24-year-old southpaw has registered an even 1-1 record and 3.27 ERA in five home starts, issuing eight walks and striking out 16 batters in 33 combined innings.  Keuchel ended up on the losing end in facing Miley last month at Chase Field. 

The MLB betting odds are a bit inflated in this contest, but it’s hard to ignore that the Diamondbacks are 15-6 in their last 21 games against left-handed starters, while the Astros have lost eight of their last nine in the same situation. 

MLB Picks:  Arizona Diamondbacks -180

San Francisco Giants at San Diego Padres 

Matt CainSan Francisco heads out on a dangerous six-game road trip against National League West rivals, as it still copes with All-Star outfielder Melky Cabrera being suspended for the remainder of the regular season following a positive test for testosterone.  San Diego is playing its best baseball of the season, and has won four of its last five home games following a road trip of seven or more days.

Giants starting pitcher Matt Cain (11-5, 2.99 ERA) snapped a personal two-game losing streak in capturing a 9-3 home win over the Colorado Rockies last time out, allowing two runs and seven hits over 7.1 innings.  The right-hander has gone 5-2 with a 3.91 ERA in 11 road starts, with opposing hitters batting .243 against him.  In 29 career starts versus the Padres, Cain has produced a 6-11 record and 3.26 ERA, including a 3-6 mark and 2.59 ERA in 14 efforts at Petco Park.

Ross Ohlendorf (4-3, 6.41 ERA) isn’t going to receive much attention at the betting windows, but must be respected due to his 2-0 record and 2.61 ERA in five home appearances (three starts).  The right-hander has failed to earn a decision in two games (one start) against the Giants, allowing four earned runs in seven combined innings. 

I recommend backing the home underdog in this divisional affair, considering the Giants have lost eight of Cain’s last 10 starts as a road favorite, including seven of eight at a price of -110 to -150. 

MLB Picks:   San Diego Padres +140