The No. 1 Ohio State Buckeyes will face the University of Texas San Antonio Road Runners, who recieved their ticket into the big dance after Wednesday's win.

The Texas San Antonio Road Runners made it to the main field of the NCAA Tournament by knocking off the Alabama State Hornets in Dayton on Wednesday. However, they have a totally different challenge coming their way in March Madness betting action on Friday afternoon, as they have to take on the Ohio State Buckeyes in Cleveland. Tipoff from Quicken Loans Arena is slated for 4:40 ET.

Ohio State Buckeyes

Depth Could Hurt Roadrunners

The only chance that a No. 16 seed probably would have had against these Buckeyes would be to be able to throw a number of different bodies at them. Truth be told, UTSA isn't lining up six guys against Ohio State's six guys and figuring out how to win, and at least if the play in game against the Hornets was any indication, that's exactly what it plans to do.

The good news is that men like Jeromie Hill and Melvin Johnson III are great scorers, while Devin Gibson can really be an outside threat. However, when you compare this to some of the bigs on the other end of the court, you have to really be intimidated. Johnson III scored a game high 29 points against Alabama State on Wednesday, while Hill had a double-double with 14 points and 11 boards. Gibson is the team's leading scorer at 16.8 PPG, but he only had 10 in the first round win against the Hornets.

High Hopes for Huge Run from Ohio State

Is there a bigger mortal lock this year than the #1 seeded Buckeyes making it into the Sweet 16? After all, this was a team that finished up with a perfect record at home this season, and now, it only has to travel up the road to Cleveland, where it should have a huge home court advantage, especially against some team from Texas.

As we alluded to before, the Buckeyes really don't substitute that much once Aaron Craft comes off of the bench and replaces Dallas Lauderdale, as Craft, Jon Diebler, Jared Sullinger, William Buford, and David Lighty always play the mass majority of the game. However, any of these men can stroke it from beyond the arc (though obviously, Sullinger is much better served in the paint), and all of them can go for 20+ points in a game if given the chance. That's what makes this team so lethal, and that's why OSU is set in the NCAA Basketball odds as a clear cut favorite to win the East Region this season.

Ohio StateBuckeyes to Lower the Boom on March Madness Odds

The first weekend of the dance is one that typically treats Head Coach Thad Matta and company well. Save that ridiculous overtime loss to the Siena Saints from two seasons back, the Buckeyes haven't been beaten in the first weekend of the dance since a second round exit to the Georgetown Hoyas in 2006.

As of publication of this article, there are no NCAA Tournament lines up on this game, but based upon the other No. 1 seeds, we can expect to see the Buckeyes favored by at least 17 points and probably fewer than 21.

Earlier this season, teams like this just never stood a chance in Columbus. Just look at some of these margins of victory... 41 vs. UNC A&T, 40 vs. UNC Wilmington, 19 vs. Morehead State, 21 vs. Miami (OH), 21 vs. IUPUI, 25 vs. Western Carolina, 28 vs. Florida Gulf Coast, 22 vs. South Carolina, 37 vs. UNC Asheville, 29 vs. Oakland, 60 vs. Tennessee Martin...

Needless to say, we're definitely circling the Buckeyes as the team to cover the spread on Friday.